Antiviral drugs

Centre for viral research

Covid-19, dengue fever, Ebola: viruses are often the root cause of devastating diseases. But medical science has not yet succeeded in developing a broad-spectrum drug – akin to an antibiotic – to treat viral infections. Now, researchers at Ecole Polytechnique Fédérale de Lausanne are aiming to develop precisely such an “antivirotic”.


The project in brief

Catch and squeeze the virus to death. Put simply, this is the principle behind the antiviral drug being developed by Francesco Stellacci and his research group at Ecole Polytechnique Fédérale de Lausanne.

Professor Francesco Stellacci envisions a two-pronged approach to treating viral infections of any kind. In addition to a broad-spectrum “antivirotic”, he plans to develop tailor-made antiviral drugs that are effective against specific viruses. During the Covid-19 pandemic, he and his team at the Supramolecular Nano-Materials and Interfaces Laboratory at the Ecole Polytechnique Fédérale de Lausanne (EPFL) were able to focus their energies on developing the antivirals – thanks to funding from the Werner Siemens Foundation. The researchers are also collaborating with virology and infectious disease specialists at the University of Geneva and the Geneva University Hospitals. The first experiments have yielded promising results, and if Stellacci’s innovative method is proven to work, he’ll receive additional funding from the Werner Siemens Foundation to establish a centre for viral research and put his approach to creating antivirals in action.


Facts and figures

Project

Francesco Stellacci is developing a broad-spectrum antiviral drug that can be used to treat a wide range of viral infections. A particular focus is on Covid-19 and other respiratory diseases caused by viruses. 

Support

The Werner Siemens Foundation is funding the project from April 2020 to March 2021. During the 12-month period, the agent is being tested on animals and in vitro, and good manufacturing practices (GMP) are being prepared. In addition, the first clinical trial will be held at the Geneva University Hospitals (HUG).

Funding from the Werner Siemens Foundation

5 million Swiss francs 

Project duration

2020 to 2021

Project leader

Prof. Dr Francesco Stellacci, Supramolecular Nano-Materials and Interfaces Laboratory, Institute of Materials, École Polytechnique Fédérale de Lausanne (EPFL), Switzerland